The following research studies are ongoing and open for enrollment for volunteers who meet the eligibility requirements. A few of the key eligibility requirements are listed below. If you are interested in possible participation, or have questions about the study, please address your inquiries to the contact person listed.

All clinical research studies in the UAB Department of Ophthalmology take place in the Callahan Eye Foundation Hospital (unless otherwise specifically noted). The hospital is at 700 18th Street South covering the entire block between University Blvd. and 7th Avenue South. We have an attached parking deck for our visitors. Those participating in research studies receive free parking. Enter the parking deck from University Blvd. For an area street map of our location, please click here.

The primary objective of AREDS2 is to evaluate the effect of the nutritional supplements lutein/zeaxanthin and/or omega -3 LCPUFAs (DHA and EPA) on progression to advanced AMD. This objective will be accomplished by collecting and assessing the data on participants aged 50 to 85 years, who at the time of enrollment have either: 1) bilateral large drusen or 2) large drusen in one eye and advanced AMD (neovascular AMD or central geographic atrophy) in the fellow eye.  An additional goal of the study is to assess whether forms of the AREDS nutritional supplement with reduced zinc and/or no beta-carotene works as well as the original supplement in reducing the risk of progression to advanced AMD.  For more information, please contact Katherine Kallies at 325-8527 or kallika@uab.edu.

Thank you for your interest! Without research volunteers, scientific progress toward developing new and improved treatments would not be possible.